Concept 37 Master genes control basic body plans.

Links

Fly Base

The web site to go to for scientists working on or looking for genetic information about Drosophila melanogaster. The genomic sequence of D. melanogaster is available, as are pictures and descriptions of fly mutations.

Fly Morph-o-Genesis

Check out these movies of early fruit fly embryonic development put together using scanning electron micrographs. Movies need the Quick Time plug-in to play.

Interactive Fly

A cyberspace guide to Drosophila genes and their roles in development.

Bibliography

• Gehring, W.J. and Hiromi, Y., 1986, Homeotic Genes and the Homeobox, Ann. Rev. Genet., 20: 147-173.
• Lewis, E.B., 1978, A Gene Complex Controlling Segmentation in Drosophila, Nature, 276: 565-570.
• Lewis, R.A. and Kaufman, T.C., Denell, R.E. and Tallerico, P., 1980, Genetic Analysis of the Antennapedia Gene Complex (ANT-C) and Adjacent Chromosomal Regions of Drosophila melanogaster. I. Polytene Chromosome Segments 84B-D, Genetics, 95: 367-381.
• Lewis, R.A., Wakimoto, B.T., Denell, R.E. and Kaufman, T.C., 1980, Genetic Analysis of the Antennapedia Gene Complex (ANT-C) and Adjacent Chromosomal Regions of Drosophila melanogaster. II. Polytene Chromosome Segments 84A-84B1.2, Genetics, 95: 383-397.
• Nüsslein-Volhard, C. and Wieschaus, E., 1980, Mutations Affecting Segmentation Number and Polarity in Drosophila, Nature, 287: 795-801.
• Passner, J.M., Ryoo, H.D., Shen, L., Mann, R.S., and Aggarwal, A.K., 1999, Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex, Nature, 397: 714-719.
• Scott, M.P., 1986, Spatial Programming of Gene Expression in Early Drosophila Embryogenesis, Ann. Rev. Cell Biol., 2: 49-80.
• Weatherbee, S.D., Halder, G., Kim, J., Hudson, A., and Carroll, S., 1998, Ultrabithorax regulates genes at several levels of the wing-patterning hierarchy to shape the development of the Drosophila haltere, Genes and Development, 12: 1474-1482.